Bruker 9.4T/30-cm Lab
The Bruker Biospec 9.4T/30-cm horizontal bore animal MRI system is a shared instrumentation originally funded by NIH S10 RR019924. The system has an ultra-shield refrigerated magnet at high magnetic field that delivers superior imaging signal-to-noise-ratio (SNR) than conventional field strength, enabling our investigators to perform anatomical, functional, and molecular MRI research at very high spatial resolution. (Please see Imaging Service) The daily operation and maintenance of the system is overseen by a group of experienced scientists at CAMRI. The system provides services primarily for in vivo rodent (rats and mice) brain studies but is also capable of imaging outside the brain as well as in different animal species or ex vivo specimens.
Technical Features
- AVANCED NEO console (surpported by S10MH124745)
- 2 broadband RF amplifiers
- 4 receive channels
- Bruker BGA-30 gradient (30 cm ID, 200 mT/m)
- RRI BFG 240/120 gradient with 12 shim channels (12 cm ID, 1000 mT/m)
- IECO 350/400 gradient amplifier
- RF interface adapter for home-made coils
- Several custom-made MR-compatible animal cradles for rats and mice
Volume Coils
- 15, 25, 35 and 86 mm quad-transceiver coils
- 1H/17O double-tuned volume coils
- Homemade 1H/19F double-tuned volume coils
Surface Coils
- 4-channel receive-only phase array rat brain coil
- Quad-receive only mouse brain coil
- 1H/13C and 1H/31P double-tuned linear transceivers
- Homemade rat (1.6–2.2 cm) and mouse (0.7–1 cm) transceiver surface coils
Arterial Spin Labeling
- Homemade rat neck labeling coil
- Homemade mouse heart labeling coil
- Homemade active coil decoupling box
Physiological Maintenance/Monitoring
- CWE MRI-1 MR-compatible ventilator
- CWE MicroCapStar MR-compatible microcapnometer
- MouseOx Plus non-invasive vital signs monitor with MR-compatible sensors (heart rate, respiration rate, and oxygen saturation)
- SAII animal respiration and ECG monitoring and gating system
- SAII MR-compatible small rodent heater system
- (2) Oakton multi-parameter temperature controller for automatic feedback animal temperature control
- Heated feedback-controlled circulating bath: Thermo Scientific SC150-S13
- Harvard Apparatus homeothermic blanket control
- Harvard Apparatus PHD 2000 Infusion pump